Clinical Application of Myocardial Perfusion SPECT in Patients with Suspected or Known Coronary Artery Disease. What Role in the Multimodality Imaging Era?

Myocardial perfusion single photon emission computed tomography (SPECT) is widely used in assessing coronary artery disease (CAD) owing to its proven efficacy extensive clinical experience. Like other functional tests, myocardial SPECT recommended for the diagnosis of obstructive CAD, risk stratification assessment, and treatment decision making. Besides quantifying left ventricular volume, global regional function by electrocardiography (ECG)-gated acquisition, can identify ischemia, scars, stunning, viable hibernating myocardium. It provides comprehensive data across spectrum CAD a cost-effective strategy patients with intermediate pre-test probability or history ischemic cardiomyopathy. With ongoing advances cardiovascular prevention factor management many referred testing now have low-to-intermediate CAD. Besides, has become chronic condition resulting from novel therapeutic strategies. Against this background, approaches combining anatomical tests sequence simultaneously include calcium score integrated imaging fusion SPECT/coronary angiography (CCTA). In review we summarize current indications integration techniques improve diagnostic performance, patient management, outcome prediction